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healthfinder.gov - Fanconi's Anemia
This consumer health information fact sheet contains basic information about Fanconi anemia including history, description of the disease and its symptoms and treatment. ... Details >
Fanconi Anemia, What Is
What Is Fanconi Anemia?
OMIM - FANCONI ANEMIA; FA
OMIM - Fanconi ANEMIA; FA
MedlinePlus Enciclopedia Médica: Anemia de Fanconi
Un trasplante de médula ósea puede curar los problemas de conteos sanguíneos de la anemia de Fanconi. La mejor fuente donante es la de un hermano compatible para HLA. Otras fuentes son las células sanguíneas del cordón umbilical y la médula ósea de personas no emparentadas. Un trasplante de médula ósea es muy efectivo y, aunque puede haber efectos secundarios del tratamiento, los cuidados de personas con anemia de Fanconi tienden a mejorar durante el trasplante. La tasa de éxito es alta para aquellas personas que encuentran un donante.
Fanconi Anemia -- GeneReviews -- NCBI Bookshelf
Genetic counseling. Mutations in the genes for all but one of the Fanconi anemia complementation groups are inherited in an autosomal recessive manner. FANCB mutations are inherited in an X-linked manner. Each sib of an individual with autosomal recessive FA has a 25% chance of inheriting both mutations and being affected, a 50% chance of inheriting one mutated gene and being a carrier, and a 25% chance of inheriting both normal genes and not being a carrier. Carriers (heterozygotes) for autosomal recessive FA are asymptomatic. Prenatal testing is available for pregnancies at 25% risk using the DEB/ MMC test on fetal cells obtained by chorionic villus sampling (CVS) at about ten to 12 weeks' gestation or amniocentesis usually performed at about 15-18 weeks' gestation. If the disease-causing mutations for FANCA , FANCB , FANCC , FANCE , FANCF , FANCG , or FANCI within a given family are known, molecular genetic testing can be used for carrier detection and prenatal testing.
Fanconi's anemia
Fanconi's anemia
Fanconi Anemia, Diagnosis
People who have Fanconi anemia (FA) are born with the disease. They may or may not show signs or symptoms of it at birth. For this reason, FA isn't always diagnosed when a person is born. In fact, most people with the disease are diagnosed between the ages of 2 and 15 years.
IBMFS - Fanconi's Anemia (FA, or Fanconi Anemia)
IBMFS - Fanconi Anemia (FA, or Fanconi Anemia)
MedlinePlus
Medical Encyclopedia: Fanconi's anemia
A bone marrow transplant can cure the blood count problems of Fanconi's anemia. A HLA matched sibling is the best donor source. Other sources are blood cells from the umbilical cord and bone marrow from an unrelated person. A bone marrow transplant is very effective. Although there can be side effects from this treatment, the care of people with Fanconi's tends to improve during the transplant. The success rate is high for people who have a donor.
Definition of Fanconi's anemia - NCI Dictionary of Cancer Terms
A rare inherited disorder in which the bone marrow does not make blood cells. It is usually diagnosed in children between 2 and 15 years old. Symptoms include frequent infections, easy bleeding, and extreme tiredness. People with Fanconi anemia may have a small skeleton and brown spots on the skin. They also have an increased risk of developing certain types of cancer.
IBMFS - links
Rosenberg PS, Alter BP, Socié G, Gluckman E: Secular Trends in Outcomes for Fanconi Anemia Patients Who Receive Transplants: Implications for Future Studies . Biology of Blood and Bone Marrow Transplantation 2005; 11:672-679.
Fanconi syndrome - Glossary Entry - Genetics Home Reference
Fanconi syndrome - Glossary Entry - Genetics Home Reference
Search of: "Fanconi's anemia" - List Results - ClinicalTrials.gov
Chronic Myeloproliferative Disorders; Diamond-Blackfan Anemia; Fanconi Anemia; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/ Myeloproliferative Diseases
Search of: "Fanconi Anemia" - List Results - ClinicalTrials.gov
Chronic Myeloproliferative Disorders; Diamond-Blackfan Anemia; Fanconi Anemia; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/ Myeloproliferative Diseases
healthfinder.gov - Fanconi's Anemia
This consumer health information fact sheet contains basic information about Fanconi anemia including history, description of the disease and its symptoms and treatment. ... Details >
Fanconi anemia type 3
Fanconi anemia type 3
Definición de anemia de Fanconi - Diccionario de cáncer
Trastorno hereditario poco frecuente en el cual la médula ósea no produce células sanguíneas. Por lo general, se diagnostica en niños entre 2 y 15 años de edad. Los síntomas incluyen infecciones frecuentes, hemorragia fácil y cansancio extremo. Las personas con la anemia de Fanconi pueden tener un esqueleto pequeño y manchas marrones en la piel. También tienen un mayor riesgo de padecer de ciertos tipos de cáncer.
Energy Citations Database (ECD) - - Document #134021
Fanconi anemia (FA) is a rare, recessive, genetically heterogeneous disease characterized by progressive insufficiency of the bone marrow and increased cellular sensitivity to DNA crosslinking agents. Complementation tests among different FA cells have indicated the presence of at least 4 FA-causing genes. One of the genes, FACC, was identified by functional complementation but appears unlikely to account for many phenotypically indistinguishable FA caes. We have begun a linkage study of FA using{open_quotes}homozygosity mapping{close_quotes}, a method that involves genotyping with DNA markers on affected individuals whose parents are related. Because FA is a rare recessive disease, it is most likely that probands are homozygous by descent at the disease locus and, therefore, at nearby DNA markers. Although the probability that any given marker will be homozygous in an inbred individual is high, given markers with moderate heterozygosities, the chance that two unrelated inbred individuals will be homozygous at the same marker is considerably lower. By locating overlapping regions of homozygosity between different families we hope to identify genes that cause FA. Sixteen consanguineous non-FACC FA families from the International Fanconi Anemia Registry at Rockefeller University are under study. An efficient algorithm for data analysis was developed and incorporated into software that can quickly compute exact multipoint lod scores using all markers on an entire chromosome. At the time of this writing, 171 of 229 microsatellite markers spaced at 20 cM intervals across the genome have been analyzed.
Fanconi's anemia
The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Fanconi's anemia. Click on the link to go to OMIM and review these resources.
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