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This article provides summary information pertaining to the disease / condition of Anemia, Aplastic. This information was extracted from selected U.S. Government resources. Links to related conditions are also provided.

congenital aplastic anemia
congenital Aplastic anemia

Search of: Open Studies | "Anemia, Aplastic" - List Results - ClinicalTrials.gov
Leukemia; Non-Hodgkin's Lymphoma; Chronic Lymphocytic Leukemia; Hodgkin's Disease; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Aplastic Anemia; Chronic Myelogenous Leukemia

MedlinePlus: Anemia
ClinicalTrials.gov: Anemia, Aplastic

MedlinePlus Medical Encyclopedia: Idiopathic aplastic anemia
The cause of idiopathic Aplastic anemia is unknown, but is thought to be an autoimmune process (the body reacting against its own cells). Causes of other types of Aplastic anemia may be chemotherapy , radiation therapy , toxins , drugs, pregnancy, inherited or congenital (present at birth) disorders, or systemic lupus erythematosus . In some cases, Aplastic anemia is associated with another blood disorder, paroxysmal nocturnal hemaglobinuria (PNH).

Aplastic Anemia - Evaluation, Treatment and Research at the National Heart, Lung and Blood Institute
Researchers at the National Heart, Lung, and Blood Institute of the National Institutes of Health, a part of the Department of Health and Human Services, are investigating methods of treatment for severe Aplastic anemia. Hematologists are comparing the effectiveness of three immunosuppressive regimens in previously untreated (no prior immunosuppressive therapy) patients. The study may help increase blood counts, reduce anemia symptoms, and/ or reduce dependence on immunosuppressive medications and transfusions. If determined eligible to participate, you (your child) will be selected by a process based on chance to receive one of threee therapies.

aplastic anemia
congenital Aplastic anemia

How Is Aplastic Anemia Treated?
In general, treatments for Aplastic anemia can limit and prevent complications, relieve symptoms, and improve quality of life. For some, a cure may be possible. Bone marrow transplants can be a cure for those people who are eligible for a transplant. Removing a known cause of Aplastic anemia (such as exposure to a toxic chemical) also can cure the disorder. Other treatments can restore blood cell counts to levels high enough so that a person can live a normal life.

healthfinder.gov - Aplastic Anemia
This section provides basic information about the bone marrow diseases, Aplastic Anemia, Myelodysplastic Syndromes, and Paroxysmal Noctural Hemoglobinuria. For more in-depth information, you can requ ... Details >

What Is Aplastic Anemia?
It is normal for blood cells to die. The lifespan of red blood cells is about 120 days. White blood cells live less than 1 day. Platelets live about 6 days. As a result, bone marrow must constantly make new blood cells. The term " anemia " is most often used to mean a condition in which a person s number of red blood cells is too low or their red blood cells do not carry enough hemoglobin (HEE-muh-glow-bin). However, in Aplastic anemia, normal production of all blood cells red cells, white cells, and platelets slows or stops. This is because the stem cells have been damaged. The cause of this damage is often unknown.

Congenital aplastic anemia
ClinicalTrials.gov lists trials that are studying or have studied Congenital Aplastic anemia. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.

FDA Drug Safety Newsletter: Postmarketing Reviews
The mean age of patients described in the case reports was 48 years (range 4 to 75). Gender distribution was slightly greater for males (56%). Ten patients received temolozomide for the approved indications of glioblastoma multiforme (5) and anaplastic astrocytoma (5). The remainder of the cases involved patients with the following reported tumors: oligodendroma (3), ependymoma (1), glioma (1), medulloblastoma (1), unspecified brain tumor (1), and in one case the underlying condition information was unknown. Eight patients received concurrent radiation treatment. The median time to onset of Aplastic anemia from the start of temozolomide therapy was 36 days (range 5 to 578). Nine cases occurred in treatment-na patients receiving temozolomide according to the labeled dose. Time of onset for these cases was 1 to 3 months after initiating therapy.

Aplastic Anemia Investigation
In response to a citizen inquiry, the Oregon Public Health Division and the Washington Department of Health led a multi-agency investigation to assess rates of Aplastic anemia and certain cancers in Columbia County, Oregon and Cowlitz County, Washington. This report also reviews the possible role of exposure to benzene from specific sources as a cause of disease in these counties.

Definition of aplastic anemia - NCI Dictionary of Cancer Terms
Definition of Aplastic anemia - NCI Dictionary of Cancer Terms

Rare Diseases Terms - Office of Rare Diseases
Rare Diseases Terms - Office of Rare Diseases

healthfinder.gov - Aplastic Anemia
The Aplastic Anemia &MDS International Foundation is the oldest and largest patient advocate and support organization for Aplastic anemia, myelodysplastic syndromes (MDS), paroxysmal nocturnal hemoglo ... Details >

Hepatitis and aplastic anemia.
Hepatitis and Aplastic anemia.

Chloramphenicol and Aplastic Anemia
Chloramphenicol and Aplastic Anemia

Blood Diseases and Cancer - Evaluation, Treatment and Research at the National Heart, Lung and Blood Institute
Researchers at the National Heart, Lung, and Blood Institute of the National Institutes of Health, a part of the Department of Health and Human Services, are investigating methods of treatment for severe Aplastic anemia. Hematologists are comparing the effectiveness of three immunosuppressive regimens in previously untreated (no prior immunosuppressive therapy) patients. The study may help increase blood counts, reduce anemia symptoms, and/ or reduce dependence on immunosuppressive medications and transfusions. If determined eligible to participate, you (your child) will be selected by a process based on chance to receive one of threee therapies.

Aplastic Crisis Publication
An Aplastic crisis is an infection caused by parvovirus B19. It causes production of red blood cells (RBC's) to be shut down for 10 days. This means that RBC's are not being made during this period. Because the RBC's in children with sickle cell anemia live only 10-15 days (compared to 120 days in children who do not have sickle cell anemia), the blood count (hemoglobin & hematocrit) drops rapidly to dangerously low levels during the infection.

Energy Citations Database (ECD) - - Document #4426985
Energy Citations Database (ECD) - - Document #4426985

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